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化合物简介
Amoscanate (INN), also known as nithiocyamine, is an experimental anthelmintic agent of the arylisothiocyanate class which was found to be highly effective in animals against the four major species of schistosomes which infect humans, and is also highly active against hookworm infection. However, significant liver toxicity was seen in lab animals at higher doses. The ether analogue of amoscanate, nitroscanate, is used in veterinary medicine as an anthelmintic.
基本信息
CAS:26328-53-0
中文别名:
英文别名:4-Isothiocyanato-N-(4-nitrophenyl)aniline;4-(4-nitroanilino)-phenylisothiocyanate;4-Nitro-4\'-isothiocyano-diphenylamin;Amoscanato [INN-Spanish];Ciba 9333 GO;4-Isothiocyanato-4\'-nitrodiphenylamine;4-(4-nitrophenyl)-aminophenylisothiocyanate;Amoscanate;Amoscanato;Amoscanatum;4-(4-Nitroanilino)phenylisothiocyanat;Nithiocyamine;Amoscanatum [INN-Latin];
分子式:C13H9N3O2S
分子量:271.294
精确质量:271.042
Psa:102.3
Logp:4.6689
中文别名:
英文别名:4-Isothiocyanato-N-(4-nitrophenyl)aniline;4-(4-nitroanilino)-phenylisothiocyanate;4-Nitro-4\'-isothiocyano-diphenylamin;Amoscanato [INN-Spanish];Ciba 9333 GO;4-Isothiocyanato-4\'-nitrodiphenylamine;4-(4-nitrophenyl)-aminophenylisothiocyanate;Amoscanate;Amoscanato;Amoscanatum;4-(4-Nitroanilino)phenylisothiocyanat;Nithiocyamine;Amoscanatum [INN-Latin];
分子式:C13H9N3O2S
分子量:271.294
精确质量:271.042
Psa:102.3
Logp:4.6689
编号系统
UNII:X0MK46CVRB
物化性质
密度:1.3g/cm3
沸点:469.7ºC at 760mmHg
闪点:237.9ºC
折射率:1.654
储存条件:库房通风低温干燥
蒸汽压:5.38E-09mmHg at 25°C
沸点:469.7ºC at 760mmHg
闪点:237.9ºC
折射率:1.654
储存条件:库房通风低温干燥
蒸汽压:5.38E-09mmHg at 25°C
安全信息
海关编码:2930909090
生产方法及用途
合成路线
上游原料
下游产品
图谱
13C NMR : Predict

1H NMR : Predict
