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Tasquinimod
4-hydroxy-5-methoxy-N,1-dimethyl-2-oxo-N-[4-(trifluoromethyl)phenyl]quinoline-3-carboxamide
化合物简介
Tasquinimod is an orally active antiangiogenic agent which may inhibit HDAC4 signalling. This affects cancer cell survival thus making this compound and anti-cancer agent.
基本信息
CAS：254964-60-8
中文别名：他喹莫德;
英文别名：Tasquinimod;4-hydroxy-5-methoxy-N,1-dimethyl-2-oxo-N-[(4-trifluoromethyl)phenyl]-1,2-dihydroquino line-3-carboxamide;N-methyl-N(4-trifluoromethyl-phenyl)-1,2-dihydro-4-hydroxy-5-methoxy-1-methyl-2-oxo-quinoline-3-carboxamide;Tasquinimod [INN];1,2-dihydro-4-hydroxy-5-methoxy-N,1-dimethyl-2-oxo-N-[4-(trifluoromethyl)phenyl]-3-quinolinecarboxamide;UNII-756U07KN1R;
分子式：C20H17F3N2O4
分子量：406.355
精确质量：406.114
Psa：71.77
Logp：3.5481
中文别名：他喹莫德;
英文别名：Tasquinimod;4-hydroxy-5-methoxy-N,1-dimethyl-2-oxo-N-[(4-trifluoromethyl)phenyl]-1,2-dihydroquino line-3-carboxamide;N-methyl-N(4-trifluoromethyl-phenyl)-1,2-dihydro-4-hydroxy-5-methoxy-1-methyl-2-oxo-quinoline-3-carboxamide;Tasquinimod [INN];1,2-dihydro-4-hydroxy-5-methoxy-N,1-dimethyl-2-oxo-N-[4-(trifluoromethyl)phenyl]-3-quinolinecarboxamide;UNII-756U07KN1R;
分子式：C20H17F3N2O4
分子量：406.355
精确质量：406.114
Psa：71.77
Logp：3.5481
编号系统
UNII：756U07KN1R
物化性质
密度：1.4±0.1g/cm3
沸点：501.5±50.0°Cat760mmHg
闪点：257.1±30.1°C
外观性状：whitesolid
蒸汽压：0.0±1.4mmHgat25°C
折射率：1.606
储存条件：-20℃
沸点：501.5±50.0°Cat760mmHg
闪点：257.1±30.1°C
外观性状：whitesolid
蒸汽压：0.0±1.4mmHgat25°C
折射率：1.606
储存条件：-20℃
安全信息
生产方法及用途
合成路线
上游原料
下游产品
图谱
13C NMR : Predict
1H NMR : Predict
