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  • 阿拉莫林

    2-amino-N-[(2R)-1-[(3R)-3-benzyl-3-[dimethylamino(methyl)carbamoyl]piperidin-1-yl]-3-(1H-indol-3-yl)-1-oxopropan-2-yl]-2-methylpropanamide

化合物简介

Anamorelin (INN) (developmental code names ONO-7643, RC-1291, ST-1291), also known as anamorelin hydrochloride (USAN, JAN), is a non-peptide, orally-active, centrally-penetrant, selective agonist of the ghrelin/growth hormone secretagogue receptor (GHSR) with appetite-enhancing and anabolic effects which is under development by Helsinn Therapeutics for the treatment of cancer cachexia and anorexia.

基本信息

CAS:249921-19-5
中文别名:(3R)-1-(2-甲基丙氨酰-D-色氨酰)-3-苯甲基-3-哌啶 1,2,2-三甲基甲酰肼;
英文别名:RC 1291;ONO7643;UNII-DD5RBA1NKF;DD5RBA1NKF;Anamorelin;
分子式:C31H42N6O3
分子量:546.704
精确质量:546.332
Psa:114.77
Logp:3.7481

编号系统

物化性质

密度:1.214

安全信息

生产方法及用途

合成路线

上游原料

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图谱

13C NMR : Predict


1H NMR : Predict


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