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化合物简介
(trans-4-Hydroxymethylcyclohexyl)carbamic Acid tert-Butyl Ester is used to prepare C-2 hydroxyethyl imidazopyrrolo pyridines as JAK1 inhibitors. It is also used to prepare Mer kinase inhibitors for treatment of pediatric acute lymphoblastic leukemia.
基本信息
CAS：239074-29-4
中文别名：反式-(4-羟基甲基)环己基氨基甲酸叔丁酯;
英文别名：N-tert-butoxy-carbonyl-trans-4-(hydroxymethyl)cyclohexylamine;trans-(4-Boc-Aminocyclohexyl)methanol;cis-(4-Boc-Aminocyclohexyl)methanol;trans-1-(Boc-Amino)-4-(hydroxymethyl)cyclohexane;tert-butyl (1r,4r)-4-(hydroxymethyl)cyclohexylcarbamate;1,1-dimethylethyl [trans-4-(hydroxymethyl)cyclohexyl]carbamate;trans (4-hydroxymethyl-cyclohexyl)-carbamic acid tert-butyl ester;tert-butyl (trans-4-(hydroxymethyl)cyclohexyl)carbamate;
分子式：C12H23NO3
分子量：229.316
精确质量：229.168
Psa：58.56
Logp：2.4531
中文别名：反式-(4-羟基甲基)环己基氨基甲酸叔丁酯;
英文别名：N-tert-butoxy-carbonyl-trans-4-(hydroxymethyl)cyclohexylamine;trans-(4-Boc-Aminocyclohexyl)methanol;cis-(4-Boc-Aminocyclohexyl)methanol;trans-1-(Boc-Amino)-4-(hydroxymethyl)cyclohexane;tert-butyl (1r,4r)-4-(hydroxymethyl)cyclohexylcarbamate;1,1-dimethylethyl [trans-4-(hydroxymethyl)cyclohexyl]carbamate;trans (4-hydroxymethyl-cyclohexyl)-carbamic acid tert-butyl ester;tert-butyl (trans-4-(hydroxymethyl)cyclohexyl)carbamate;
分子式：C12H23NO3
分子量：229.316
精确质量：229.168
Psa：58.56
Logp：2.4531
编号系统
MDL号：MFCD03844605
物化性质
密度：1.05g/cm3
沸点：351.603ºC at 760 mmHg
闪点：166.444ºC
折射率：1.485
蒸汽压：0mmHg at 25°C
沸点：351.603ºC at 760 mmHg
闪点：166.444ºC
折射率：1.485
蒸汽压：0mmHg at 25°C
安全信息
海关编码：2924299090
生产方法及用途
合成路线
上游原料
下游产品
图谱
13C NMR : Predict
1H NMR : Predict
