trans-1,2-Cyclohexanedicarboxylic Acid is used as a reagent in the synthesis of enantiopure (α-cyanoalkyl)(tetrahydropyrido[4,3-b]indolecarbonyl)cyclohexanecarboxamides and its analogs as selective cathepsin K inhibitors for the treatment of osteoarthritis. Also used as a reagent in the synthesis of novel cyclopentanedicarboxamide sodium channel blockers as a potential treatment for chronic pain.

CAS：2305-32-0
中文别名：1,2-环己二甲酸;环己二酸;反-环己二甲酸;反式-1,2-环己烷二酸;反-1,2-环己二羧酸;反-六氢邻苯二甲酸;
英文别名：TRANS-CYCLOHEXANE-1,2-DICARBOXYLIC ACID;trans-1,2-Cyclohexanedicarboxylic Acid;TRANS-HEXAHYDRO-PHTHALIC ACID;1,2-trans-cyclohexane-dicarboxylic acid;TRANS-1,2-CYCLOHEXANEDICARBOXYLIC ACDI;trans-Cyclohexane-1,2-dicarboxylic acid,trans-Hexahydrophthalic acid;trans-Hexahydrophthalic acid;1,2-Cyclohexanedicarboxylic acid, trans-;trans-Cyclohexane-1,2-dicarboxylic acid;1,2-cyclohexanedicarboxylic;rac-trans-cyclohexane-1,2-dicarboxylic acid;Trans-1,2-cyclohexane carboxylic acid;
分子式：C8H12O4
分子量：172.178
精确质量：172.074
Psa：74.6
Logp：0.962

EINECS号：218-975-8
RTECS号：GU9065000
PubChem号：24848558
BRN号：3200609
MDL号：MFCD00001464

外观与性状：白色结晶粉末
密度：1.314 g/cm3
沸点：384.1ºC at 760 mmHg
熔点：228-230°C(lit.)
闪点：200.3ºC
稳定性：Stable under normal temperatures and pressures.
储存条件：Store in a tightly closed container. Store in a cool, dry, well-ventilated area away from incompatible substances.
蒸汽压：5.78E-07mmHg at 25°C

RTECS号：GU9065000
安全说明：S26-S36
WGK Germany：3
危险类别码：R36/37/38
海关编码：29172000
危险品标志：Xi
危险标志：GHS07
危险性防范说明：P261; P305 + P351 + P338
危险性描述：H315; H319; H335
信号词：Warning