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化合物简介
5-Bromothiophene 2-Oxoacetic Acid Ethyl Ester is a useful synthetic intermediate in the synthesis of 5-Bromothiophene 2-Oxoacetic Acid; a reagent used in the synthesis of N-quinuclidinyl amides for use in therapy as M3 muscarinic receptor antagonists.
基本信息
CAS:22098-10-8
中文别名:
英文别名:ethyl 2-(5-bromothien-2-yl)-2-oxoacetate;ethyl 2-(5-bromothienyl)glyoxalate;(5-bromo-thiophen-2-yl)-oxo-acetic acid ethyl ester;Ethyl 2-(5-bromothiophen-2-yl)-2-oxoacetate;Ethyl 2-(5-bromo-2-thienyl)-2-oxoacetate;ethyl (5-bromo-thien-2-yl)glyoxylate;ethyl (5-bromo-2-thienyl)glyoxylate;
分子式:C8H7BrO3S
分子量:263.108
精确质量:261.93
Psa:71.61
Logp:2.2564
中文别名:
英文别名:ethyl 2-(5-bromothien-2-yl)-2-oxoacetate;ethyl 2-(5-bromothienyl)glyoxalate;(5-bromo-thiophen-2-yl)-oxo-acetic acid ethyl ester;Ethyl 2-(5-bromothiophen-2-yl)-2-oxoacetate;Ethyl 2-(5-bromo-2-thienyl)-2-oxoacetate;ethyl (5-bromo-thien-2-yl)glyoxylate;ethyl (5-bromo-2-thienyl)glyoxylate;
分子式:C8H7BrO3S
分子量:263.108
精确质量:261.93
Psa:71.61
Logp:2.2564
编号系统
物化性质
密度:1.612g/cm3
沸点:325ºC at 760mmHg
熔点:70-72ºC
闪点:150.3ºC
折射率:1.568
蒸汽压:0.000237mmHg at 25°C
沸点:325ºC at 760mmHg
熔点:70-72ºC
闪点:150.3ºC
折射率:1.568
蒸汽压:0.000237mmHg at 25°C
安全信息
安全说明:S26-S37/39
危险类别码:R36/37/38
海关编码:2934999090
危险品标志:Xi
危险类别码:R36/37/38
海关编码:2934999090
危险品标志:Xi
生产方法及用途
合成路线
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参考文献
Unterhalt; Gores Archiv der Pharmazie, 1989 , vol. 322, # 11 p. 839 - 840
上游原料
下游产品
图谱
13C NMR : Predict
1H NMR : Predict



