Clothianidin is an insecticide developed by Takeda Chemical Industries and Bayer AG. Similar to thiamethoxam and imidacloprid, it is a neonicotinoid. Neonicotinoids are a class of insecticides that are chemically similar to nicotine, which has been used as a pesticide since the late 1700s. Clothianidin and other neonicotinoids act on the central nervous system of insects as an agonist of acetylcholine, the neurotransmitter that stimulates nAChR, targeting the same receptor site (AChR) and activating post-synaptic acetylcholine receptors but not inhibiting AChE. Clothianidin and other neonicotinoids were developed to last longer than nicotine, which is more toxic and which breaks down too quickly in the environment. However, studies published in 2012 show that neonicotinoid dust released at planting time may persist in nearby fields for several years and be taken up into non-target plants, which are then foraged by bees and other insects.; Clothianidin is an alternative to organophosphate, carbamate, and pyrethroid pesticides. It poses lower risks to mammals, including humans, when compared to organophosphates and carbamates. It has helped prevent insect pests build up resistance to organophosphate and pyrethroid pesticides.

CAS：210880-92-5
中文别名：(E)-1-(2-氯-1,3-噻唑-5-基甲基)-3-甲基-2-硝基胍;噻虫胺;(E)-1-(2-氯-5-噻唑基甲基)-3-甲基-2-硝基胍;
英文别名：3-(2-chloro-5-thiazolylmethyl)-1-methyl-2-nitroguanidine;Apacz;1-[(2-chloro-5-thiazolyl)methyl]-3-methyl-2-nitroguanidine;Belay;Pancho;Poncho;Dantotsu;Dantop;(E)-1-(2-chlorothiazol-5-ylmethyl)-3-methyl-2-nitroguanidine;TI 435;Clutch;Celero;N-(2-chloro-5-thiazolylmethyl)-3-methyl-2-nitro-guanidine;1-(2-chlorothiazol-5-ylmethyl)-2-nitro-3-methyl-guanidine;
分子式：C6H8ClN5O2S
分子量：249.678
精确质量：249.009
Psa：123.37
Logp：1.9582

MDL号：MFCD06200753
RTECS号：ME9565000

密度：1.61
沸点：435.2ºC at 760mmHg
熔点：178.8 °C
闪点：217ºC
折射率：1.709
水溶解性：327 MG/L AT 20 ºC
储存条件：0-6ºC
蒸汽压：8.93E-08mmHg at 25°C

RTECS号：ME9565000
安全说明：S26; S36; S36/37/39; S22
危险类别码：R22; R36/37/38; R20/21/22
WGK Germany：3
危险品运输编码：UN2811
海关编码：2934100016
危险类别：6.1
包装等级：III
危险品标志：Xn; Xi

用途
噻虫胺是新烟碱类中的一种杀虫剂，是一类高效安全、高选择性的新型杀虫剂，其作用与烟碱乙酰胆碱受体类似，具有触杀、胃毒和内吸活性。