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乙基甲基-氨基甲酸 (3R)-2,3-二氢-3-(2-丙炔氨基)-1H-茚-5-基酯酒石酸盐
(2R,3R)-2,3-dihydroxybutanedioic acid,[(3R)-3-(prop-2-ynylamino)-2,3-dihydro-1H-inden-5-yl] N-ethyl-N-methylcarbamate
化合物简介
A novel brain-selective MAO inhibitor, Ladostigil can selectively reverse the behavioral and neurochemical effects induced by prenatal stress without affecting the behavior of controls. Antidepressant .
基本信息
CAS：209394-46-7
中文别名：
英文别名：UNII-2J1346C51H;Ladostigil Tartrate;ethylmethylcarbamic acid (3R)-2,3-dihydro-3-(2-propynylamino)-1H-inden-5-yl ester (2R,3R)-2,3-dihydroxybutanedioate;R(+)-6-(N-methyl-N-ethylcarbamoyloxy)-N\'-propargyl-1-aminoindan tartrate;R(+)-6-(N-methyl-N-ethylcarbamoyloxy)-N\'-propargyl-1-aminoindan L-tartrate;(3R)-3-(prop-2-ynylamino)-2,3,-dihydro-1H-indan-5-yl ethyl methyl carbamate tartrate;TV-3219;[(3R)-3-(prop-2-ynylamino)-2,3-dihydro-1H-inden-5-yl] N-ethyl-N-methylcarbamate;(2R,3R)-2,3-dihydroxybutanedioic acid;ethyl-methyl-carbamic acid (R)-3-prop-2-ynylamino-indan-5-yl ester tartrate;TV-3326;
分子式：C36H46N4O10
分子量：694.771
精确质量：694.321
Psa：198.2
Logp：3.3536
中文别名：
英文别名：UNII-2J1346C51H;Ladostigil Tartrate;ethylmethylcarbamic acid (3R)-2,3-dihydro-3-(2-propynylamino)-1H-inden-5-yl ester (2R,3R)-2,3-dihydroxybutanedioate;R(+)-6-(N-methyl-N-ethylcarbamoyloxy)-N\'-propargyl-1-aminoindan tartrate;R(+)-6-(N-methyl-N-ethylcarbamoyloxy)-N\'-propargyl-1-aminoindan L-tartrate;(3R)-3-(prop-2-ynylamino)-2,3,-dihydro-1H-indan-5-yl ethyl methyl carbamate tartrate;TV-3219;[(3R)-3-(prop-2-ynylamino)-2,3-dihydro-1H-inden-5-yl] N-ethyl-N-methylcarbamate;(2R,3R)-2,3-dihydroxybutanedioic acid;ethyl-methyl-carbamic acid (R)-3-prop-2-ynylamino-indan-5-yl ester tartrate;TV-3326;
分子式：C36H46N4O10
分子量：694.771
精确质量：694.321
Psa：198.2
Logp：3.3536
编号系统
UNII：2J1346C51H
物化性质
沸点：412.4ºC at 760 mmHg
闪点：203.2ºC
蒸汽压：5.19E-07mmHg at 25°C
闪点：203.2ºC
蒸汽压：5.19E-07mmHg at 25°C
安全信息
生产方法及用途
合成路线
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参考文献
Aronhime, Judith; Bahar, Eliezer; Frenkel, Anton; Gottesfeld, Ronen; Gold, Amir; Koltai, Tamas Patent: US2007/88082 A1, 2007 ; Location in patent: Page/Page column 13 ;
上游原料
下游产品
图谱
1H NMR : Predict
13C NMR : Predict
