N-Boc-trans-4-fluoro-L-proline is a useful synthetic intermediate. It is used to prepare potent 3- or 4-substituted-2-cyanopyrrolidine dipeptidyl peptidase IV inhibitors. It is also used to synthesize pyrrolotriazines derivatives as pan-Aurora kinase inhibitors and anti-tumor agents.

CAS：203866-14-2
中文别名：(2S,4R)-N-(叔丁氧基羰基)-反式-4-氟-L-脯氨酸;N-(叔丁氧羰基)-反-4-氟-L-脯氨酸;(2S,4R)-1-(叔丁氧基羰基)-4-氟-2-吡咯烷羧酸;N-叔丁氧羰基-反式-4-氟-L-脯氨酸;(2S,4R)-1-Boc-4-氟-2-吡咯烷羧酸;
英文别名：(2S,4R)-1-(tert-Butoxycarbonyl)-4-fluoro-2-pyrrolidinecarboxylic Acid;1-(tert-butoxycarbonyl)-(4R)-fluoropyrrolidine-(2S)-carboxylic acid;trans-4-Fluoro-L-proline,N-BOC protected;(4R)-1-(tert-butoxycarbonyl)-4-fluoro-L-proline;Boc-trans-4-Fluoro-L-proline;N-Boc-trans-4-fluoro-L-proline;(2S,4R)-1-(tert-Butoxycarbonyl)-4-fluoropyrrolidine-2-carboxylic acid;N-(tert-Butoxycarbonyl)-(2S,4R)-4-fluoroproline;Boc-trans-4F-Pro;(2S,4R)-4-fluoro-1,2-pyrrolidinedicarboxylic acid 1,1-dimethylethylester;N-(tert-Butoxycarbonyl)-trans-4-fluoro-L-proline;(2S,4R)-N-Boc-4-fluoroproline;(2S,4R)-1-Boc-4-fluoro-2-pyrrolidinecarboxylic Acid;(2S,4R)-1-(tert-butoxycarbonyl)-4-fluoropyrrolidine-2-carboxylic acid;(2S,4R)-4-Fluoropyrrolidine-1,2-dicarboxylic acid 1-tert-butyl ester;
分子式：C10H16FNO4
分子量：233.237
精确质量：233.106
Psa：66.84
Logp：1.3564

MDL号：MFCD06796085

密度：1.24 g/cm3
沸点：346ºCat 760 mmHg
熔点：115-119ºC
闪点：163ºC
蒸汽压：1.05E-05mmHg at 25°C

安全说明：S26-S36/37
危险类别码：R36/37/38
海关编码：2933990090
危险品标志：Xi
危险性防范说明：P261; P305 + P351 + P338
危险性描述：H315; H319; H335
危险标志：GHS07
信号词：Warning