3-Chloro-5-fluorophenol is a useful synthetic intermediate. It was used to prepare substituted amides as antagonists and/or inverse agonists of cannabinoid-1 receptor. It was also used to synthesize substituted N-(arylmethyl)aryloxy arylcarboxamide and heteroarylcarboxamide antagonists for the PGE2 receptor EP4 for the treatment of pain, inflammation, osteoarthritis, and rheumatoid arthritis.

CAS：202982-70-5
中文别名：
英文别名：3-chloranyl-5-fluoranyl-phenol;3-chloro-5-fluoro-phenol;
分子式：C6H4ClFO
分子量：146.547
精确质量：145.993
Psa：20.23
Logp：2.1847

MDL号：MFCD00042212

密度：1.408g/cm3
沸点：206ºC at 760mmHg
闪点：78.4ºC
折射率：1.537
蒸汽压：0.17mmHg at 25°C

安全说明：S26-S36/37/39
危险类别码：R20/21/22
海关编码：2908199090
危险品标志：Xi