Janex 1 is a Janus tyrosine kinase 3 (JAK3) inhibitor. Inhibition of JAK3 has been shown to exhibit protective action against the development of T1D in non-obese diabetic (NOD) mice. Janex 1 has been shown to suppresses proliferation of short-term cultured NOD CD4+ T cells through induction of apoptosis, while promoting survival of a particular population of long-term cultured cells. It ameliorates the expression of TNF-α-induced cell adhesion molecules and improves myocardial vascular permeability.

CAS：202475-60-3
中文别名：
英文别名：1-Amino-4-<4-hydroxy-anilino>-anthrachinon-2-sulfonsaeure;
分子式：C16H15N3O3
分子量：297.309
精确质量：297.111
Psa：76.5
Logp：3.1692

MDL号：MFCD01862614

密度：1.3±0.1g/cm3
沸点：468.1±40.0°Cat760mmHg
闪点：236.9±27.3°C
外观性状：lightyellowsolid
蒸汽压：0.0±1.2mmHgat25°C
折射率：1.689
储存条件：-20℃