An intermediate in the formation of L-egothioneine, a natural amino acid ubiquitously present in cells and tissues of most plants and mammalian species. In humans, L-ergothioneine is found in red blood cells, liver, kidney, brain, seminal fluid, and cataract-free lenses at concentrations ranging from 100 uM to 2 mM. L-ergothioneine is exclusively biosynthesized in fungi and mycobacteria. Hence, humans assimilate it through dietary intake.\n\nL-ergothioneine has been proven to act as an antioxidant in vivo and to afford protection from g and UV radiation as well as from singlet oxygen in vivo. Recently, it has been shown that L-ergothioneine protects isolated perfused heart against the deleterious effect of post-ischemic reperfusion.\n\nThe intermediate, 2-mercaptohistine has been used for the introduction of conformational constraints into peptides via thioether linkage and for the preparation of the bactericidal products in combination with penicillanic acid and with cephalosporin derivatives.

CAS：2002-22-4
中文别名：2-疏基-l-组氨酸;
英文别名：(S)-2-Amino-3-(2-thioxo-2,3-dihydro-1H-imidazol-4-yl)propanoic acid;(2S)-2-amino-3-(2-sulfanylidene-1,3-dihydroimidazol-4-yl)propanoic acid;
分子式：C6H9N3O2S
分子量：187.22
精确质量：187.042
Psa：130.8
Logp：0.3531

UNII：MH6EDB26P8

密度：1.52g/cm3
沸点：376.3ºC at 760mmHg
熔点：320-325ºC
闪点：181.4ºC
折射率：1.695
储存条件：-15ºC
蒸汽压：1.06E-06mmHg at 25°C

海关编码：2933290090