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  • 2-[(4-硝基苯基)氨基]乙醇

    2-(4-nitroanilino)ethanol

化合物简介

2-[(4-nitrophenyl)amino]ethanol is used to prepare phenylpurinediamine derivatives as a class of reversible kinase inhibitors targeting both EGFR-activating and resistance mutations of lung cancer. It is also used to synthesize benzannulated N-heterocycles via palladium-catalyzed domino intermolecular alkylation/intramolecular amination of functionalized aryl iodides and bromoalkylamines.

基本信息

CAS:1965-54-4
中文别名
英文别名
分子式:C8H10N2O3
分子量:182.177
精确质量:182.069
Psa:78.08
Logp:1.5952

编号系统

物化性质

密度:1.352g/cm3
沸点:389.5ºC at 760mmHg
闪点:189.4ºC
折射率:1.64
蒸汽压:9.13E-07mmHg at 25°C

安全信息

海关编码:2922199090

生产方法及用途

合成路线

上游原料

下游产品

图谱

13C NMR : Predict


1H NMR : Predict


Mass


IR : nujol mull


IR : KBr disc


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