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化合物简介
2-[(4-nitrophenyl)amino]ethanol is used to prepare phenylpurinediamine derivatives as a class of reversible kinase inhibitors targeting both EGFR-activating and resistance mutations of lung cancer. It is also used to synthesize benzannulated N-heterocycles via palladium-catalyzed domino intermolecular alkylation/intramolecular amination of functionalized aryl iodides and bromoalkylamines.
基本信息
CAS:1965-54-4
中文别名:
英文别名:
分子式:C8H10N2O3
分子量:182.177
精确质量:182.069
Psa:78.08
Logp:1.5952
中文别名:
英文别名:
分子式:C8H10N2O3
分子量:182.177
精确质量:182.069
Psa:78.08
Logp:1.5952
编号系统
物化性质
密度:1.352g/cm3
沸点:389.5ºC at 760mmHg
闪点:189.4ºC
折射率:1.64
蒸汽压:9.13E-07mmHg at 25°C
沸点:389.5ºC at 760mmHg
闪点:189.4ºC
折射率:1.64
蒸汽压:9.13E-07mmHg at 25°C
安全信息
海关编码:2922199090
生产方法及用途
合成路线
上游原料
下游产品
图谱
13C NMR : Predict

1H NMR : Predict

Mass

IR : nujol mull

IR : KBr disc
