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化合物简介
Pipamperone (INN, USAN, BAN), also known as carpiperone and floropipamide or fluoropipamide, and as floropipamide hydrochloride (JAN), is a typical antipsychotic of the butyrophenone family used in the treatment of schizophrenia. It is or has been marketed under brand names including Dipiperon, Dipiperal, Piperonil, Piperonyl, and Propitan. Pipamperone was discovered at Janssen Pharmaceutica in 1961, and entered clinical trials in the United States in 1963.
基本信息
CAS:1893-33-0
中文别名:氟丙哌隆;
英文别名:Dipiperal;piperonil;floropipamide;MCN-JR-3345;Dipiperon;Pipamperone;R 3345;Piperonyl;Propitan;Floropipamid;PIPAMPERONE DIHYDROCHLORIDE APPROX. 99;1\'-[4-(4-fluoro-phenyl)-4-oxo-butyl]-octahydro-[1,4\']bipyridinyl-4\'-carboxylic acid amide;FPA;Dipiperone;1\'-[3-(p-fluorobenzoyl)propyl]-[1,4\'-bipiperidine]-4\'-carboxamide;
分子式:C21H30FN3O2
分子量:375.48
精确质量:375.232
Psa:66.64
Logp:3.1705
中文别名:氟丙哌隆;
英文别名:Dipiperal;piperonil;floropipamide;MCN-JR-3345;Dipiperon;Pipamperone;R 3345;Piperonyl;Propitan;Floropipamid;PIPAMPERONE DIHYDROCHLORIDE APPROX. 99;1\'-[4-(4-fluoro-phenyl)-4-oxo-butyl]-octahydro-[1,4\']bipyridinyl-4\'-carboxylic acid amide;FPA;Dipiperone;1\'-[3-(p-fluorobenzoyl)propyl]-[1,4\'-bipiperidine]-4\'-carboxamide;
分子式:C21H30FN3O2
分子量:375.48
精确质量:375.232
Psa:66.64
Logp:3.1705
编号系统
UNII:5402501F0W
物化性质
密度:1.174g/cm3
沸点:563.7ºC at 760 mmHg
闪点:294.7ºC
折射率:1.556
蒸汽压:9.88E-13mmHg at 25°C
沸点:563.7ºC at 760 mmHg
闪点:294.7ºC
折射率:1.556
蒸汽压:9.88E-13mmHg at 25°C
安全信息
危险类别码:R22
WGK Germany:1
海关编码:2933399090
危险品标志:Xn
WGK Germany:1
海关编码:2933399090
危险品标志:Xn
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1H NMR : Predict

13C NMR : Predict
