3α-Androstanediol (often abbreviated as 3α-diol), also known as 5α-androstane-3α,17β-diol, is an endogenous inhibitory androstane neurosteroid and weak androgen, and a major metabolite of dihydrotestosterone (DHT). As a neurosteroid, it acts as a potent positive allosteric modulator of the GABAA receptor, and has been found to have rewarding, anxiolytic, pro-sexual, and anticonvulsant effects. As androgens such as testosterone and DHT are known to have many of the same effects as 3α-diol and are converted into it in vivo, it is thought that this compound may in part be responsible for said effects. Relative to its isomer 3β-androstanediol, which is a potent estrogen, 3α-androstanediol has substantially lower, though still significant affinity for the estrogen receptors, with a several-fold preference for ERβ over ERα.

CAS：1852-53-5
中文别名：3Α,17-二羟基-5Β-雄甾烷;5A-雄甾烷-3A 17B-二醇;雄烷二羟基;5α-雄甾烷-3α,17β-二醇;3α,17β-Dihydroxy-5α-androstane;
英文别名：5a-androstane-3a,17b-diol;5A-ANDROSTAN-3A,17SS-DIOL;5A-androstane-3A,17B-diol;dihydroandrosterone;5alpha-androstane-3alpha,17beta-diol;DIHYDROANDROSTANEDIOL;[3H]-Hombreol;Hombreol;Etiocholane-3alpha,17beta-diol;Androstane-3,17-diol, (3α,5α,17β);Androstane-3alpha,17beta-diol;5-ANDROSTANEDIOL;5.α.-Androstane-3.α.,17.β.-androstanediol;5A-ANDROSTAN-3A,17B-DIOL;
分子式：C19H32O2
分子量：292.456
精确质量：292.24
Psa：40.46
Logp：3.7509

UNII：J34MX0M30Y

密度：1.09g/cm3
沸点：415ºC at 760 mmHg
折射率：1.546
蒸汽压：1.27E-08mmHg at 25°C