Valdecoxib is a non-steroidal anti-inflammatory drug (NSAID) used in the treatment of osteoarthritis, rheumatoid arthritis, and painful menstruation and menstrual symptoms. It is a selective cyclooxygenase-2 inhibitor.

CAS：181695-72-7
中文别名：4-(5-甲基-3-苯基-4-异噁唑)苯磺酰胺;伐地昔布杂质;甲溴后马托品;4-(5-甲基-3-苯基-1,2-恶唑-4-基)苯磺酰胺;伐地昔布;
英文别名：4-(5-methyl-3-phenylisoxazol-4-yl)benzensulfonamide;4-(5-methyl-3-phenyl-1,2-oxazol-4-yl)benzenesulfonamide;4-(5-Methyl-3-phenyl-4-isoxazolyl)benzenesulfonamide;Kudeq;Bextra;Valdecoxib(R);4-[5-methyl-3-phenylisoxazol-4-yl ] benzenesulfonamide;4-(4-sulfamoylphenyl)-5-methyl-3-phenyl-isoxazole;Valdecoxib;[14C]-Valdecoxib;Valdyn;
分子式：C16H14N2O3S
分子量：314.359
精确质量：314.073
Psa：94.57
Logp：4.7455

MDL号：MFCD00950568

外观与性状：白色结晶粉末
密度：1.303 g/cm3
沸点：481.2ºC at 760 mmHg
熔点：162-164ºC
闪点：244.8ºC
折射率：1.608
蒸汽压：2.03E-09mmHg at 25°C

海关编码：2935009090
危险标志：GHS08, GHS09
危险性防范说明：P273; P281; P501
危险性描述：H361d; H373; H410
信号词：Warning

用途
帕瑞昔布钠中间体。