(R)-1-Phenyl-1,2,3,4-tetrahydroisoquinoline is the counterpart to (S)-1-Phenyl-1,2,3,4-tetrahydroisoquinoline, the latter enantiomer being a key intermediate in the preparation of Solifenacin, an antimuscarinic agent. Since (R)-1-Phenyl-1,2,3,4-tetrahydroisoquinoline is produced as a by-product, it has been suggested that it should be recycled in order to obtain the S enantiomer on a larger scale. (R)-1-Phenyl-1,2,3,4-tetrahydroisoquinoline is also used as a reagent to prepare quinuclidin-3-yl 1,2,3,4-tetrahydroisoquinoline-2-carboxylate derivatives, compounds that act as muscarinic receptor antagonists.

CAS：180272-45-1
中文别名：(1R)-1-苯基-1,2,3,4-四氢异喹啉;
英文别名：(R)-1-Phenyl-1,2,3,4-tetrahydroisoquinoline;
分子式：C15H15N
分子量：209.286
精确质量：209.12
Psa：12.03
Logp：3.2505

密度：1.065 g/cm3
沸点：338.4ºC at 760 mmHg
闪点：166.9ºC