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化合物简介

2-(5-Hexynyloxy)tetrahydro-2H-pyran is used as a reagent to synthesize (-)-Pyrinodemin A, a cytotoxic pyridine alkaloid that is isolated from an Okinawan marine sponge (Amphimedon sp.). 2-(5-Hexynyloxy)tetrahydro-2H-pyran is also used as a reagent to synhesize (+)-Lycoricidine, an alkaloid that has antimitotic activity.

基本信息

CAS:1720-37-2
中文别名
英文别名:6-(oxacyclohex-2-yloxy)hex-1-yne;rac-6-[(tetrahydro-2H-pyran-2-yl)oxy]-1-hexyne;2-(hex-5-yn-1-yloxy)tetrahydro-2h-pyran;1-(tetrahydropyran-2\'-yloxy)hex-5-yne;1-(tetrahydropyran-2-yloxy)-5-hexyne;2-(5-hexynyloxy)tetrahydro-2H-pyran;
分子式:C11H18O2
分子量:182.259
精确质量:182.131
Psa:18.46
Logp:2.3331

编号系统

物化性质

密度:0.96g/cm3
沸点:266ºC at 760mmHg
闪点:97.8ºC
折射率:1.462
蒸汽压:0.0146mmHg at 25°C

安全信息

生产方法及用途

合成路线

上游原料

下游产品

图谱

13C NMR : Predict


1H NMR : Predict


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