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  • 4-苯基丁酸钠盐

    sodium phenylbutyrate

化合物简介

Sodium phenylbutyrate is a salt of an aromatic fatty acid, 4-phenylbutyrate (4-PBA) or 4-phenylbutyric acid. The compound is used to treat urea cycle disorders, because its metabolites offer an alternative pathway to the urea cycle to allow excretion of excess nitrogen. It is an orphan drug, marketed by Ucyclyd Pharma under the trade name Buphenyl, by Swedish Orphan International (Sweden) as Ammonaps, and by Fyrlklövern Scandinavia as triButyrate.

基本信息

CAS:1716-12-7
中文别名
英文别名:Sodium 4-phenylbutyrate;Sodium phenylbutyrate;4-PBA,4-Phenylbutyric acid,4-phenylbutyrate;
分子式:C10H11NaO2
分子量:186.183
精确质量:186.066
Psa:40.13
Logp:0.7592

编号系统

UNII:NT6K61736T

物化性质

密度:1.095g/cm3
沸点:290.7ºC at 760mmHg
熔点:207°C (dec.)(lit.)
闪点:187.9ºC
储存条件:Desiccate at -20ºC
蒸汽压:0.00288mmHg at 25°C

安全信息

RTECS号:XJ1921000
安全说明:S26; S36
危险类别码:R36/37/38
WGK Germany:3
海关编码:2916399090
危险品标志:Xi
危险性描述:H319
危险标志:GHS07
危险性防范说明:P305 + P351 + P338
信号词:Warning

生产方法及用途

用途
医药中间体和其它精细化工产品

合成路线

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图谱

Predict 1H proton NMR


13C NMR : Predict


1H NMR : Predict


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