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  • 3-溴-2-氟苯甲酸

    3-Bromo-2-fluorobenzoic acid

化合物简介

3-Bromo-2-fluorobenzoic acid is used as a reagent to synthesize Dabrafenib, an inhibitor of BRAF kinase that is used to treat BRAF V600-mutation positive carcinoma. BRAF is a gene that mediates cell growth and is activated by mutations caused by cancer. 3-Bromo-2-fluorobenzoic acid is also used as a reagent to prepare Alkynlphenoxyacetic acid receptor agonists, compounds that can be potentially used for the treatment of allergic inflammatory diseases (such as allergic rhinitis).

基本信息

CAS:161957-56-8
中文别名:2-氟-3-溴苯甲酸;
英文别名:2-fluoro-3-bromobenzoic acid;3-Bromo-2-Fluorobenzoic acid;3-Bromo-2-fluoro-benzoic acid;
分子式:C7H4BrFO2
分子量:219.008
精确质量:217.938
Psa:37.3
Logp:2.2864

编号系统

MDL号:MFCD00665763

物化性质

熔点:168 °C

安全信息

海关编码:2916399090
危险品标志:Xi

生产方法及用途

合成路线

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图谱

Predict 1H proton NMR


13C NMR : Predict


1H NMR : Predict


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