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化合物简介

Cromoglicic acid (INN) (also referred to as cromolyn (USAN), cromoglycate (former BAN), or cromoglicate) is traditionally described as a mast cell stabilizer, and is commonly marketed as the sodium salt sodium cromoglicate or cromolyn sodium. This drug prevents the release of inflammatory chemicals such as histamine from mast cells.

基本信息

CAS:16110-51-3
中文别名:4H-1-苯并吡喃-2-甲酸,5,5\'-[(2-羟基-1,3-丙烷二基)双(氧基)]双[4-氧代;
英文别名:Acidum cromoglicicum;cromolyn;Nalcrom;Acide cromoglicique;Cromolyn;1,3-bis(2-carboxychromon-5-yloxy)-2-hydroxy propane;5-[3-(2-carboxy-4-oxochromen-5-yl)oxy-2-hydroxypropoxy]-4-oxochromene-2-carboxylic acid;1,3-bis(2-carboxy-chromon-5-yloxy)-propan-2-ol;Cromoglicic acid;Cromoglycate;Acido cromoglicico;5,5\'-(2-hydroxypropane-1,3-diyl)bis(oxy)bis(4-oxo-4H-chromene-2-carboxylic acid);Lomusol;Lomudal;
分子式:C23H16O11
分子量:468.367
精确质量:468.069
Psa:173.71
Logp:2.1145

编号系统

MDL号:MFCD00864784

物化性质

外观与性状:吸湿的白色粉末
密度:1.623
沸点:752.3ºC at 760 mmHg
熔点:241-242ºC
闪点:263.9ºC
折射率:1.681
稳定性:Very stable with no degradation under normal storage conditions except for moisture gain.
储存条件:Keep in a cool, dry, dark location in a tightly sealed container or cylinder. Keep away from incompatible materials, ignition sources and untrained individuals. Secure and label area. Protect containers/cylinders from physical damage.
蒸汽压:1.08E-23mmHg at 25°C

安全信息

RTECS号:DJ2380000
安全说明:S26; S36
危险类别码:R36/37/38
WGK Germany:2
海关编码:2922499990
危险品标志:Xi

生产方法及用途

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图谱

Predict 1H proton NMR


13C NMR : Predict


1H NMR : Predict


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