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化合物简介
Almotriptan (trade names Axert (US, Canada), Almogran (Belgium, Denmark, Finland, France, Germany, Italy, Ireland Portugal, Spain, the United Kingdom, the Netherlands, Sweden, Switzerland, South Korea… ), Almotrex (Italy) and Amignul (Spain)) is a triptan drug discovered and developed by Almirall for the treatment of heavy migraine headache. It is available in 12.5mg in most countries and also 6.25mg in US and Canada.
基本信息
CAS:154323-57-6
中文别名:N,N-二甲基-2-(5-((吡咯烷-1-基磺酰基)甲基)-1H-吲哚-3-基)乙胺;阿莫曲坦;
英文别名:Axert;UNII-1O4XL5SN61;Almotriptan;Almogran;N,N-dimethyl-2-[5-(pyrrolidin-1-ylsulfonylmethyl)-1H-indol-3-yl]ethanamine;
分子式:C17H25N3O2S
分子量:335.464
精确质量:335.167
Psa:64.79
Logp:3.2163
中文别名:N,N-二甲基-2-(5-((吡咯烷-1-基磺酰基)甲基)-1H-吲哚-3-基)乙胺;阿莫曲坦;
英文别名:Axert;UNII-1O4XL5SN61;Almotriptan;Almogran;N,N-dimethyl-2-[5-(pyrrolidin-1-ylsulfonylmethyl)-1H-indol-3-yl]ethanamine;
分子式:C17H25N3O2S
分子量:335.464
精确质量:335.167
Psa:64.79
Logp:3.2163
编号系统
MDL号:MFCD00927104
物化性质
密度:1.27 g/cm3
沸点:538.7ºC at 760 mmHg
闪点:279.6ºC
沸点:538.7ºC at 760 mmHg
闪点:279.6ºC
安全信息
海关编码:2935009090
生产方法及用途
用途
抗偏头痛药。
抗偏头痛药。
合成路线
上游原料
下游产品
图谱
13C NMR : Predict

1H NMR : Predict
