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甲基6-[1-(3,5,5,8,8-五甲基-5,6,7,8-四氢-2-萘基)环丙基]烟酸酯
methyl 6-[1-(3,5,5,8,8-pentamethyl-6,7-dihydronaphthalen-2-yl)cyclopropyl]pyridine-3-carboxylate
化合物简介
A RXR selective retinoid.
基本信息
CAS：153559-50-3
中文别名：
英文别名：6-[1-(5,6,7,8-Tetrahydro-3,5,5,8,8-pentamethyl-2-naphthalenyl)cyclopropyl]-3-pyridinecarboxylic Acid Methyl Ester;methyl 6-[(3,5,8,8-pentamethyl-5,6,7,8-tetrahydronaphthalen-2-yl)cyclopropyl]nicotinate;METHYL 6-(1-(1,2,3,4-TETRAHYDRO-1,1,4,4,6-PENTAMETHYLNAPHTHALEN-7-YL)CYCLOPROPYL)PYRIDINE-3-CARBOXYLATE;methyl 6-<1-(3,5,5,8,8-pentamethyl-5,6,7,8-tetrahydronaphthalen-2-yl)cyclopropyl>nicotinate;AmbkkkkK609;methyl 6-[(3,5,5,8,8-pentamethyl-5,6,7,8-tetrahydronaphthalen-2-yl)cyclopropyl]nicotinate;6-[(3,5,5,8,8-Pentamethyl-5,6,7,8-tetrahydronaphthalen-2-yl)cyclopropyl] Nicotinic Acid Methyl Ester;
分子式：C25H31NO2
分子量：377.519
精确质量：377.235
Psa：39.19
Logp：5.6055
中文别名：
英文别名：6-[1-(5,6,7,8-Tetrahydro-3,5,5,8,8-pentamethyl-2-naphthalenyl)cyclopropyl]-3-pyridinecarboxylic Acid Methyl Ester;methyl 6-[(3,5,8,8-pentamethyl-5,6,7,8-tetrahydronaphthalen-2-yl)cyclopropyl]nicotinate;METHYL 6-(1-(1,2,3,4-TETRAHYDRO-1,1,4,4,6-PENTAMETHYLNAPHTHALEN-7-YL)CYCLOPROPYL)PYRIDINE-3-CARBOXYLATE;methyl 6-<1-(3,5,5,8,8-pentamethyl-5,6,7,8-tetrahydronaphthalen-2-yl)cyclopropyl>nicotinate;AmbkkkkK609;methyl 6-[(3,5,5,8,8-pentamethyl-5,6,7,8-tetrahydronaphthalen-2-yl)cyclopropyl]nicotinate;6-[(3,5,5,8,8-Pentamethyl-5,6,7,8-tetrahydronaphthalen-2-yl)cyclopropyl] Nicotinic Acid Methyl Ester;
分子式：C25H31NO2
分子量：377.519
精确质量：377.235
Psa：39.19
Logp：5.6055
编号系统
物化性质
密度：1.075g/cm3
沸点：462.471ºC at 760 mmHg
闪点：233.494ºC
折射率：1.555
蒸汽压：0mmHg at 25°C
沸点：462.471ºC at 760 mmHg
闪点：233.494ºC
折射率：1.555
蒸汽压：0mmHg at 25°C
安全信息
生产方法及用途
合成路线
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参考文献
Jurutka, Peter W.; Kaneko, Ichiro; Yang, Joanna; Bhogal, Jaskaran S.; Swierski, Johnathon C.; Tabacaru, Christa R.; Montano, Luis A.; Huynh, Chanh C.; Jama, Rabia A.; Mahelona, Ryan D.; Sarnowski, Joseph T.; Marcus, Lisa M.; Quezada, Alexis; Lemming, Brittney; Tedesco, Maria A.; Fischer, Audra J.; Mohamed, Said A.; Ziller, Joseph W.; Ma, Ning; Gray, Geoffrey M.; Van Der Vaart, Arjan; Marshall, Pamela A.; Wagner, Carl E. Journal of Medicinal Chemistry, 2013 , vol. 56, # 21 p. 8432 - 8454
上游原料
下游产品
图谱
13C NMR : Predict
1H NMR : Predict
