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化合物简介
Quinestrol (INN, USAN, BAN) (brand names Agalacto-Quilea, Basaquines, Eston, Estrovis, Estrovister, Plestrovis, Qui-lea), also known as ethinyl estradiol 3-cyclopentyl ether, is a synthetic, steroidal estrogen used in hormone replacement therapy and occasionally to treat breast cancer and prostate cancer.
基本信息
CAS:152-43-2
中文别名:炔雌醚;
英文别名:Quinestrol;17α-Ethynylestradiol 3-Cyclopentyl Ether;(8R,9S,13S,14S,17R)-3-cyclopentyloxy-17-ethynyl-13-methyl-7,8,9,11,12,14,15,16-octahydro-6H-cyclopenta[a]phenanthren-17-ol;
分子式:C25H32O2
分子量:364.52
精确质量:364.24
Psa:29.46
Logp:5.2284
中文别名:炔雌醚;
英文别名:Quinestrol;17α-Ethynylestradiol 3-Cyclopentyl Ether;(8R,9S,13S,14S,17R)-3-cyclopentyloxy-17-ethynyl-13-methyl-7,8,9,11,12,14,15,16-octahydro-6H-cyclopenta[a]phenanthren-17-ol;
分子式:C25H32O2
分子量:364.52
精确质量:364.24
Psa:29.46
Logp:5.2284
编号系统
RTECS号:RC8948000
PubChem号:24894659
EINECS号:205-803-1
MDL号:MFCD00079189
PubChem号:24894659
EINECS号:205-803-1
MDL号:MFCD00079189
物化性质
外观与性状:晶体
密度:1.15 g/cm3
沸点:502.5ºC at 760 mmHg
熔点:107 - 108ºC
闪点:218.8ºC
折射率:1.596
稳定性:Stable at normal temperatures and pressures.
蒸汽压:6.43E-11mmHg at 25°C
密度:1.15 g/cm3
沸点:502.5ºC at 760 mmHg
熔点:107 - 108ºC
闪点:218.8ºC
折射率:1.596
稳定性:Stable at normal temperatures and pressures.
蒸汽压:6.43E-11mmHg at 25°C
安全信息
RTECS号:RC8948000
安全说明:S53-S22-S36/37/39-S45
危险类别码:R46; R61; R20/21/22
WGK Germany:3
危险品标志:T
安全说明:S53-S22-S36/37/39-S45
危险类别码:R46; R61; R20/21/22
WGK Germany:3
危险品标志:T
生产方法及用途
用途
用作雌激素类药。
用作雌激素类药。
合成路线
-
参考文献
Steroids, , vol. 2, p. 387 - 392
上游原料
下游产品
图谱
Predict 1H proton NMR
13C NMR : Predict
1H NMR : Predict




