Bicine is an organic compound used as a buffering agent. It is one of Good's buffers and has a pKa of 8.35 at 20 °C. It is prepared by the reaction of glycine with ethylene oxide, followed by hydrolysis of the resultant lactone.

CAS：150-25-4
中文别名：N,N- 二-羟乙基甘氨酸;N,N-双(2-羟乙基)甘氨酸;N,N-二-羟乙基甘氨酸;二羟乙甘胺酸;N,N-双(2-羟乙基)甘氨酸(Bicine);二乙醇甘氨酸;N,N-二(2-羟乙基)甘氨酸;N-二（2-羟乙基）甘氨酸;
英文别名：N,N-Bis(2-hydroxyethyl)glycine,BICINE,PEG Grid Screening;2-[bis(2-hydroxyethyl)amino]acetic acid;Diethylolglycine;N,N-Dihydroxyethyl glycine;Bicine;BICINE[N,N-Di(2-hydroxyethyl)glycine];BICINE buffer;Bicene;N,N-Di(2-hydroxyethyl)glycine;N,N-Di(2-hydroxyethyl)glycine [Good\'s buffer component;N,N-Bis(2-hydroxyethyl)glycine;Diethanol glycine;N,N-Bis(2-hydroxyethyl)glycine (Bicine);Glycine, N,N-bis(2-hydroxyethyl)-;Diethanolglycine;Dihydroxyethylglycine;
分子式：C6H13NO4
分子量：163.172
精确质量：163.084
Psa：81.0
Logp：-1.6424

EINECS号：205-755-1
RTECS号：MB9700000
MDL号：MFCD00004295
PubChem号：24891738
BRN号：1769362

外观与性状：白色结晶粉末
密度：1.05g/mLat 20°C
沸点：388.5ºC at 760mmHg
熔点：190°C (dec.)(lit.)
闪点：188.8ºC
水溶解性：soluble
稳定性：Stable at room temperature in closed containers under normal storage and handling conditions.
储存条件：2-8ºC

RTECS号：MB9700000
安全说明：S24/25
WGK Germany：3
危险类别码：R20/21/22
海关编码：29225000
危险品标志：Xn

用途
在生化研究中用作缓冲剂