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化合物简介
Doripenem is an ultra-broad-spectrum injectable antibiotic. It is a beta-lactam and belongs to the subgroup of carbapenems. It was launched by Shionogi Co. of Japan under the brand name Finibax in 2005 and is being marketed outside Japan by Johnson & Johnson. It is particularly active against Pseudomonas aeruginosa. The usual form is doripenem monohydrate.
基本信息
CAS:148016-81-3
中文别名:多利培南;(+)-(4R,5S,6S)-6-[(1R)-1-羟基乙基]-4-甲基-7-氧代-3-[[(3S,5S)-5-[(氨基磺酰氨基)-甲基]-3-吡咯烷基]硫]-1-氮杂双环[3.2.0]庚-2-烯-2-甲酸;
英文别名:S 4661;InterMediates of DoripeneM;
分子式:C15H24N4O6S2
分子量:420.504
精确质量:420.114
Psa:195.74
Logp:0.8356
中文别名:多利培南;(+)-(4R,5S,6S)-6-[(1R)-1-羟基乙基]-4-甲基-7-氧代-3-[[(3S,5S)-5-[(氨基磺酰氨基)-甲基]-3-吡咯烷基]硫]-1-氮杂双环[3.2.0]庚-2-烯-2-甲酸;
英文别名:S 4661;InterMediates of DoripeneM;
分子式:C15H24N4O6S2
分子量:420.504
精确质量:420.114
Psa:195.74
Logp:0.8356
编号系统
MDL号:MFCD02092739
物化性质
外观与性状:白色至灰白色粉末
密度:1.59 g/cm3
沸点:694.8ºC at 760 mmHg
熔点:>186ºC dec.
闪点:374ºC
折射率:1.68
密度:1.59 g/cm3
沸点:694.8ºC at 760 mmHg
熔点:>186ºC dec.
闪点:374ºC
折射率:1.68
安全信息
生产方法及用途
合成路线
上游原料
下游产品
图谱
Predict 1H proton NMR

13C NMR : Predict

1H NMR : Predict
