Methyl (3R)-3-(tert-Butyldimethylsilanyloxy)-5-oxo-6-(triphenylphosphanylidene)hexanoate was used to preapre pyrimidinyl- and pyrrolylheptenoates with HMG-CoA reductase inhibitory activities.

CAS：147118-35-2
中文别名：(3R)-3-特丁基二甲硅基-5-氧代-6-三苯基磷烯己酸甲酯;(3R)-3-特丁基二甲硅基-5-氧代-6-三苯基磷烯己酸甲酯(J6);(3R)-叔丁基二甲硅氧基-5-氧代-6-三苯基磷烯乙酸甲酯 J-6;瑞舒伐他汀,J6;
英文别名：B-8;METHYL (3R)-3-(TERT-BUTYLDIMETHYL SILYLOXY)-5-OXO-6-TRIPHENYL PHOSPHORANYLIDENE HEXANOATE (J6);(R)-3-[[(1,1-dimethylethyl)dimethylsilyl]oxo]-5-oxo-6-(triphenylphosphoranylidene)-methyl hexanoate;methyl (3R)-3[[tert-butyl-(dimethyl)silyl]oxy]-5-oxo-6-(triphenylphosphoranylidine)hexanoate;rosuvastatin interMediates J-6;3-(tert-butyldimethylsilanyloxy)-5-oxo-6-(triphenylphosphanylidene)hexanoic acid methyl ester;methyl (3R)-3-(tert-butyldimethylsilyloxy)-5-oxo-6-(triphenylphosphoranylidene)hexanoate;(3R)-3-(tert-butyldiMethylsilyloxy)-5-oxo-6-triphenylphosphoranylidenehexanoate Methyl ester;methyl-(3R)-3-[(terbutyldimethylsilyloxy)-5-oxo-6-triphenylphosphoranylidene hexanoate;
分子式：C31H39O4PSi
分子量：534.698
精确质量：534.236
Psa：62.41
Logp：5.6954

EINECS号：604-562-3

外观与性状：淡黄色至白色结晶粉末
密度：1.1 g/cm3
沸点：603.9ºC at 760 mmHg
熔点：77.5-78.5ºC
闪点：319ºC

用途
医药中间体，是降血脂药物罗素伐他汀的主要原料。