化学科研者一站式服务平台


  • 双苯拉林

    diphenylpyraline

化合物简介

Diphenylpyraline (DPP; sold as Allergen, Arbid, Belfene, Diafen, Hispril, Histyn, Lergobine, Lyssipol, Mepiben, Neargal) is a first-generation antihistamine with anticholinergic effects of the diphenylpiperidine class. It is marketed in Europe for the treatment of allergies. DPP has also been found to act as a dopamine reuptake inhibitor and produces hyperactivity in rodents. It has been shown to be useful in the treatment of Parkinsonism.

基本信息

CAS:147-20-6
中文别名:4-(二苯基甲氧基)-1-甲基哌啶;
英文别名:4-Benzhydryloxy-1-methyl-piperidin;Lergobine;Dayfen;4-Diphenylmethoxy-1-methyl-piperidin;Allergen;Belfene;4-benzhydryloxy-1-methylpiperidine;4-benzhydryloxy-1-methyl-piperidine;4-(diphenylmethoxy)-1-methylpiperidine;Histyn;Mepiben;Hispril;N-methyl-4-(diphenylmethoxy)piperidine;Lyssipoll;Neargal;
分子式:C19H23NO
分子量:281.392
精确质量:281.178
Psa:12.47
Logp:3.8247

编号系统

EINECS号:205-686-7

物化性质

密度:1.08 g/cm3
沸点:378.7ºC at 760 mmHg
闪点:111.6ºC
折射率:1.587
蒸汽压:6.18E-06mmHg at 25°C

安全信息

危险品运输编码:UN 3249
海关编码:2933399090
危险类别:6.1(b)
包装等级:III

生产方法及用途

合成路线

上游原料

下游产品

图谱

13C NMR : Predict


1H NMR : Predict


加载中...