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化合物简介
Diphenylpyraline (DPP; sold as Allergen, Arbid, Belfene, Diafen, Hispril, Histyn, Lergobine, Lyssipol, Mepiben, Neargal) is a first-generation antihistamine with anticholinergic effects of the diphenylpiperidine class. It is marketed in Europe for the treatment of allergies. DPP has also been found to act as a dopamine reuptake inhibitor and produces hyperactivity in rodents. It has been shown to be useful in the treatment of Parkinsonism.
基本信息
CAS:147-20-6
中文别名:4-(二苯基甲氧基)-1-甲基哌啶;
英文别名:4-Benzhydryloxy-1-methyl-piperidin;Lergobine;Dayfen;4-Diphenylmethoxy-1-methyl-piperidin;Allergen;Belfene;4-benzhydryloxy-1-methylpiperidine;4-benzhydryloxy-1-methyl-piperidine;4-(diphenylmethoxy)-1-methylpiperidine;Histyn;Mepiben;Hispril;N-methyl-4-(diphenylmethoxy)piperidine;Lyssipoll;Neargal;
分子式:C19H23NO
分子量:281.392
精确质量:281.178
Psa:12.47
Logp:3.8247
中文别名:4-(二苯基甲氧基)-1-甲基哌啶;
英文别名:4-Benzhydryloxy-1-methyl-piperidin;Lergobine;Dayfen;4-Diphenylmethoxy-1-methyl-piperidin;Allergen;Belfene;4-benzhydryloxy-1-methylpiperidine;4-benzhydryloxy-1-methyl-piperidine;4-(diphenylmethoxy)-1-methylpiperidine;Histyn;Mepiben;Hispril;N-methyl-4-(diphenylmethoxy)piperidine;Lyssipoll;Neargal;
分子式:C19H23NO
分子量:281.392
精确质量:281.178
Psa:12.47
Logp:3.8247
编号系统
EINECS号:205-686-7
物化性质
密度:1.08 g/cm3
沸点:378.7ºC at 760 mmHg
闪点:111.6ºC
折射率:1.587
蒸汽压:6.18E-06mmHg at 25°C
沸点:378.7ºC at 760 mmHg
闪点:111.6ºC
折射率:1.587
蒸汽压:6.18E-06mmHg at 25°C
安全信息
危险品运输编码:UN 3249
海关编码:2933399090
危险类别:6.1(b)
包装等级:III
海关编码:2933399090
危险类别:6.1(b)
包装等级:III
生产方法及用途
合成路线
上游原料
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图谱
13C NMR : Predict

1H NMR : Predict
