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  • phenyl (1S,3S,4S,5R)-8-methyl-3-(4-methylphenyl)-8-azabicyclo[3.2.1]octane-4-carboxylate

化合物简介

(–)-2β-Carbophenoxy-3β-(p-tolyl)tropane (RTI-4229-120) is a phenyltropane derivative which acts as a reasonably selective dopamine reuptake inhibitor, along with weaker inhibition of noradrenaline and serotonin reuptake. It has a reasonably fast rate of occupancy of dopamine transporters in the brain, though slower than that of cocaine itself. RTI-120 has a short duration of action, along with other p-methyl substituted phenyltropanes such as RTI-150, RTI-171 and RTI-199, giving it a more similar pharmacological profile to cocaine compared to longer acting analogues like RTI-121 and RTI-177.

基本信息

CAS:146145-20-2
中文别名
英文别名:RTI-120;
分子式:C22H25NO2
分子量:335.439
精确质量:335.189
Psa:29.54
Logp:4.1048

编号系统

物化性质

安全信息

生产方法及用途

合成路线

上游原料

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图谱

1H NMR : Predict


13C NMR : Predict


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