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methyl ((S)-2-((2S,4S)-2-(4-(5'-chloro-4'-(6-((R)-2-methyl-4-pivaloylpiperazin-1-yl)nicotinamido)-2'-(trifluoromethoxy)-[1,1'-biphenyl]-4-yl)-1H-imidazol-2-yl)-4-methylpyrrolidin-1-yl)-2-oxo-1-(tetrahydro-2H-pyran-4-yl)ethyl)carbamate
化合物简介
基本信息
CAS：1433281-14-1
中文别名：
英文别名：[(S)-2-((2S,4S)-2-{4-[5 ({6-[(R)-4-(2,2-dimethyl-propionyl)-2-methyl-piperazin-1-yl]-pyridine-3-carbonyl}-amino)-2\'-trifluoromethoxy-biphenyl-4-yl]-1H-imidazol-2-yl}-4-methyl-pyrrolidin-1-yl)-2-oxo-1-(tetrahydro-pyran-4-yl)-ethyl]-carbamic acid methyl ester;[(S)-2-((2S,4S)-2-{4-[5\'-chloro-4\'-({6-[(R)-4-(2,2-dimethylpropionyl)-2-methylpiperazin-1-yl]-pyridine-3-carbonyl}amino)-2\'-trifluoromethoxybiphenyl-4-yl]-1H-imidazol-2-yl}-4-methylpyrrolidin-1-yl)-2-oxo-1-(tetrahydropyran-4-yl)ethyl]-carbamic acid methyl ester;
分子式：C46H54ClF3N8O7
分子量：923.419
精确质量：922.376
Psa：171.32
Logp：8.4916
中文别名：
英文别名：[(S)-2-((2S,4S)-2-{4-[5 ({6-[(R)-4-(2,2-dimethyl-propionyl)-2-methyl-piperazin-1-yl]-pyridine-3-carbonyl}-amino)-2\'-trifluoromethoxy-biphenyl-4-yl]-1H-imidazol-2-yl}-4-methyl-pyrrolidin-1-yl)-2-oxo-1-(tetrahydro-pyran-4-yl)-ethyl]-carbamic acid methyl ester;[(S)-2-((2S,4S)-2-{4-[5\'-chloro-4\'-({6-[(R)-4-(2,2-dimethylpropionyl)-2-methylpiperazin-1-yl]-pyridine-3-carbonyl}amino)-2\'-trifluoromethoxybiphenyl-4-yl]-1H-imidazol-2-yl}-4-methylpyrrolidin-1-yl)-2-oxo-1-(tetrahydropyran-4-yl)ethyl]-carbamic acid methyl ester;
分子式：C46H54ClF3N8O7
分子量：923.419
精确质量：922.376
Psa：171.32
Logp：8.4916
编号系统
物化性质
安全信息
生产方法及用途
合成路线
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参考文献
LONG, Daniel D.; MCKINNELL, Robert Murray; JIANG, Lan; LOO, Mandy; LEPACK, Kassandra; VAN ORDEN, Lori Jean; OGAWA, Gavin; HUANG, Xiaojun; ZHANG, Weijiang Patent: US2013/115194 A1, 2013
