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  • 曲美苄胺

    N-[[4-[2-(dimethylamino)ethoxy]phenyl]methyl]-3,4,5-trimethoxybenzamide

化合物简介

Trimethobenzamide (trade names Tebamide, Tigan) is an antiemetic used to prevent nausea and vomiting. It is often prescribed for patients with gastroenteritis, medication-induced nausea, and other illnesses. Trimethobenzamide is generally considered the most potent antiemetic that does not have effects on the serotonergic, dopaminergic, or histaminergic systems, so it has a lower likelihood of causing undesired side effects. In the United States, it requires a prescription.

基本信息

CAS:138-56-7
中文别名:4-(2-二甲基氨基乙氧基)-N-(3,4,5-三甲氧基苯甲酰)苄胺;甲氧安控喷;
英文别名:Tribenzagan;Trimethobenzamidum;Trimazide;Tigan;trimethobenzamide;Stemetic;Benzacot;Trimethobenzamid;Trimetobenzamida;Tebamide;
分子式:C21H28N2O5
分子量:388.457
精确质量:388.2
Psa:69.26
Logp:2.9737

编号系统

EINECS号:205-332-1

物化性质

密度:1.131 g/cm3
沸点:506.9ºC at 760 mmHg
闪点:260.4ºC
蒸汽压:2.13E-10mmHg at 25°C

安全信息

海关编码:2924299090

生产方法及用途

合成路线

上游原料

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图谱

1H NMR : Predict


13C NMR : Predict


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