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化合物简介
1-(tert-Butoxycarbonyl)-2-indolinecarboxylic Acid is used to prepare benzopyranyl indoline analogs as cardioselective anti-ischemic ATP-sensitive potassium channel openers. It is also used in the synthesis of 1,2,3,4-tetrahydroisoquinoline derivatives as potent and selective M2 muscarinic receptor antagonists.
基本信息
CAS：137088-51-8
中文别名：
英文别名：N-Boc-indoline-2-carboxylic acid;indole-1-carboxylic acid tert-butyl ester;1-Boc-indoline-2-carboxylic acid;1-t-butoxycarbonyl-2,3-dihydroindole-2-carboxylic acid;N-Boc-indole;1-tert-butoxycarbonylindole;1-boc-indole;tert-Butyl 1-indolecarboxylate;N-tert-butoxycarbonylindoline-2-carboxylate;tert-butyl N-indolecarboxylate;N-Boc-1H-indole;tert-Butyl 1H-indole-1-carboxylate;
分子式：C14H17NO4
分子量：263.289
精确质量：263.116
Psa：66.84
Logp：2.5024
中文别名：
英文别名：N-Boc-indoline-2-carboxylic acid;indole-1-carboxylic acid tert-butyl ester;1-Boc-indoline-2-carboxylic acid;1-t-butoxycarbonyl-2,3-dihydroindole-2-carboxylic acid;N-Boc-indole;1-tert-butoxycarbonylindole;1-boc-indole;tert-Butyl 1-indolecarboxylate;N-tert-butoxycarbonylindoline-2-carboxylate;tert-butyl N-indolecarboxylate;N-Boc-1H-indole;tert-Butyl 1H-indole-1-carboxylate;
分子式：C14H17NO4
分子量：263.289
精确质量：263.116
Psa：66.84
Logp：2.5024
编号系统
物化性质
密度：1.259g/cm3
沸点：411.6ºC at 760mmHg
熔点：121-122ºC
闪点：202.7ºC
沸点：411.6ºC at 760mmHg
熔点：121-122ºC
闪点：202.7ºC
安全信息
生产方法及用途
合成路线
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参考文献
Kwak, Jae-Hwan; Kim, Yoseob; Park, Hyunjeong; Jang, Jae-Yong; Lee, Keun Kuk; Yi, Wonhui; Kwak, Jeong-Ah; Park, Song-Gyu; Kim, Hwanmook; Lee, Kiho; Kang, Jong Soon; Han, Sang-Bae; Hwang, Bang Yeon; Hong, Jin Tae; Jung, Jae-Kyung; Kim, Youngsoo; Cho, Jungsook; Lee, Heesoon Bioorganic and Medicinal Chemistry Letters, 2010 , vol. 20, # 15 p. 4620 - 4623
上游原料
下游产品
图谱
13C NMR : Predict
1H NMR : Predict
