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  • methyl (1S,3S,4S,5R)-3-(4-bromophenyl)-8-methyl-8-azabicyclo[3.2.1]octane-4-carboxylate

化合物简介

(–)-2β-Carbomethoxy-3β-(4-bromophenyl)tropane (RTI-4229-51, bromopane) is a semi-synthetic alkaloid in the phenyltropane group of psychostimulant compounds. First publicized in the 1990s, it has not been used enough to have gained a fully established profile. RTI-51 can be expected to have properties lying somewhere in between RTI-31 and RTI-55. Importantly it has a ratio of monoamine reuptake inhibition of D > S > N (1.8:10.6:37.4nM respectively) which is an unusual balance of effects not produced by other commonly used compounds (although RTI-121 is similar, but more DAT selective). It has been used in its 76Br radiolabelled form to map the distribution of dopamine transporters in the brain.

基本信息

CAS:135367-08-7
中文别名
英文别名:RTI-51;
分子式:C16H20BrNO2
分子量:338.24
精确质量:337.068
Psa:29.54
Logp:3.1263

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物化性质

安全信息

生产方法及用途

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图谱

13C NMR : Predict


1H NMR : Predict


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