化学科研者一站式服务平台


  • 马扎哌汀

    piperidin-1-yl-[3-[[4-(2-propan-2-yloxyphenyl)piperazin-1-yl]methyl]phenyl]methanone

化合物简介

Mazapertine (RWJ-37796) is an antipsychotic agent that was developed by Johnson & Johnson but never marketed. It exerts its pharmacological effect through affinity for dopamine D2, serotonin 5-HT1A, and α1-adrenergic receptors.

基本信息

CAS:134208-17-6
中文别名
英文别名:UNII-N0X1XW704P;[3-[[4-[2-(1-Methylethoxy)phenyl]-1-piperazinyl]methyl]benzoyl]-piperidine;Mazapertine;Mazapertine [INN];1-[3-[[4-[2-(1-methylethoxy)phenyl]-1-piperazinyl]methyl]benzoyl]piperidine;
分子式:C26H35N3O2
分子量:421.575
精确质量:421.273
Psa:36.02
Logp:4.3629

编号系统

物化性质

密度:1.128g/cm3
沸点:583.8ºC at 760 mmHg
闪点:306.9ºC
折射率:1.584
蒸汽压:1.29E-13mmHg at 25°C

安全信息

生产方法及用途

合成路线

上游原料

下游产品

图谱

13C NMR : Predict


1H NMR : Predict


加载中...