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化合物简介
Ospemifene (commercial name Osphena produced by Shionogi) is an oral medication indicated for the treatment of dyspareunia– pain during sexual intercourse– encountered by some women, more often in those who are post-menopausal. Ospemifene is a selective estrogen receptor modulator (SERM) acting similarly to an estrogen on the vaginal epithelium, building vaginal wall thickness which in turn reduces the pain associated with dyspareunia. Dyspareunia is most commonly caused by \"vulval and vaginal atrophy.\"; The medication was approved by the FDA in February 2013.
基本信息
CAS:128607-22-7
中文别名:
英文别名:FC-1271a;Osphena;Fc-1271;Deamino-hydroxytoremifene;Ospemifene;UNII-B0P231ILBK;
分子式:C24H23ClO2
分子量:378.891
精确质量:378.139
Psa:29.46
Logp:5.6457
中文别名:
英文别名:FC-1271a;Osphena;Fc-1271;Deamino-hydroxytoremifene;Ospemifene;UNII-B0P231ILBK;
分子式:C24H23ClO2
分子量:378.891
精确质量:378.139
Psa:29.46
Logp:5.6457
编号系统
UNII:B0P231ILBK
物化性质
密度:1.166g/cm3
沸点:544.6ºC at 760 mmHg
闪点:283.2ºC
折射率:1.607
蒸汽压:1.08E-12mmHg at 25°C
沸点:544.6ºC at 760 mmHg
闪点:283.2ºC
折射率:1.607
蒸汽压:1.08E-12mmHg at 25°C
安全信息
生产方法及用途
合成路线
上游原料
下游产品
图谱
1H NMR : Predict

13C NMR : Predict
