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  • 疣孢青霉原

    verruculogen

化合物简介

Verruculogen is a mycotoxin produced by certain strains of aspergillus that belongs to a class of naturally occurring 2,5-diketopiperazines. It is an annulated analogue of cyclo(L-Trp-L-Pro) which belongs to the most abundant and structurally diverse class of tryptophan-proline 2,5-diketopiperazine natural products. It produces tremors in mice due to its neurotoxic properties. It also tested positive in a Salmonella/mammalian microsome assay and was shown to be genotoxic. It is a potent blocker of calcium-activated potassium channels.

基本信息

CAS:12771-72-1
中文别名:震颤真菌毒素;
英文别名:VERRUCULOGEN;VERRUCULOGEN FROM PENICILLIUM VERRUCULOS;TR-1TOXIN;tr1;3h)-dione,1,10,10a,14,14a,15b-hexahydro-10,10a-dihydroxy-7-methoxy-2,2-dimeth;VERRUCOLOGEN;Verruculogenresearch grade;
分子式:C27H35N3O7
分子量:513.583
精确质量:513.248
Psa:112.01
Logp:1.5959

编号系统

RTECS号:JH4920000

物化性质

外观与性状:白色粉末
密度:1.49 g/cm3
沸点:738.4ºC at 760 mmHg
熔点:233ºC
闪点:400.3ºC
折射率:1.691
储存条件:2-8ºC
蒸汽压:6.85E-23mmHg at 25°C

安全信息

安全说明:36/37/39-45
危险类别码:R23/24/25
危险品运输编码:UN 2811 6.1/PG 2
危险品标志:T

生产方法及用途

合成路线

上游原料

下游产品

图谱

13C NMR : Predict


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