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化合物简介
Oxetacaine (INN, also known as oxethazaine) is a potent local anesthetic. It is administered orally (usually in combination with an antacid) for the relief of pain associated with peptic ulcer disease or esophagitis. It is also used topically in the management of hemorrhoid pain. Oral oxetacaine preparations are available in several countries, including India, South Africa, Japan and Brazil, but not the United States.
基本信息
CAS:126-27-2
中文别名:2-双(N-甲基-N-苯基叔丁基-氨基甲酰甲基)氨基乙醇;阿塞赛因;
英文别名:2-[2-hydroxyethyl-[2-[methyl-(2-methyl-1-phenylpropan-2-yl)amino]-2-oxoethyl]amino]-N-methyl-N-(2-methyl-1-phenylpropan-2-yl)acetamide;
分子式:C28H41N3O3
分子量:467.643
精确质量:467.315
Psa:64.09
Logp:3.2401
中文别名:2-双(N-甲基-N-苯基叔丁基-氨基甲酰甲基)氨基乙醇;阿塞赛因;
英文别名:2-[2-hydroxyethyl-[2-[methyl-(2-methyl-1-phenylpropan-2-yl)amino]-2-oxoethyl]amino]-N-methyl-N-(2-methyl-1-phenylpropan-2-yl)acetamide;
分子式:C28H41N3O3
分子量:467.643
精确质量:467.315
Psa:64.09
Logp:3.2401
编号系统
PubChem号:24898016
MDL号:MFCD00079202
EINECS号:204-780-5
RTECS号:AC3325000
MDL号:MFCD00079202
EINECS号:204-780-5
RTECS号:AC3325000
物化性质
外观与性状:白色粉末
密度:1.093 g/cm3
沸点:630.4ºC at 760 mmHg
熔点:104-105°C
闪点:335.1ºC
折射率:1.557
储存条件:Keep in a cool, dry, dark location in a tightly sealed container or cylinder. Keep away from incompatible materials, ignition sources and untrained individuals. Secure and label area. Protect containers/cylinders from physical damage.
蒸汽压:9.25E-17mmHg at 25°C
密度:1.093 g/cm3
沸点:630.4ºC at 760 mmHg
熔点:104-105°C
闪点:335.1ºC
折射率:1.557
储存条件:Keep in a cool, dry, dark location in a tightly sealed container or cylinder. Keep away from incompatible materials, ignition sources and untrained individuals. Secure and label area. Protect containers/cylinders from physical damage.
蒸汽压:9.25E-17mmHg at 25°C
安全信息
RTECS号:AC3325000
安全说明:S36
WGK Germany:3
危险类别码:R22
危险品标志:Xn
安全说明:S36
WGK Germany:3
危险类别码:R22
危险品标志:Xn
生产方法及用途
合成路线
上游原料
下游产品
图谱
13C NMR : Predict

1H NMR : Predict

13C NMR : in CDCl3

1H NMR : 400 MHz in CDCl3

Mass

IR : nujol mull

IR : KBr disc
