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  • 3,3-二(4-羟基苯基)-2(3H)-吲哚酮

    3,3-bis(4-hydroxyphenyl)-1H-indol-2-one

化合物简介

Oxyphenisatine (or oxyphenisatin) is a laxative. It is closely related to bisacodyl, sodium picosulfate, and phenolphthalein. Long term use is associated with liver damage, and as a result, it was withdrawn in most countries in the early 1970s. The acetate derivative oxyphenisatine acetate was also once used as a laxative.

基本信息

CAS:125-13-3
中文别名:酚汀;3,3-双(对羟基苯基)氧化吲哚;
英文别名:Isatinbisphenol;Propellax;3,3-bis-(4-hydroxyphenyl)-2-indolinone;Hoscolax;Oxyphenisatin;3,3-bis-(4-hydroxy-phenyl)-1,3-dihydro-indol-2-one;Neodrast;Diphenolisatin;3,3-bis(4\'-hydroxyphenyl)-2-oxo-2,3-dihydroindole;Phenolisatin;Normalax;Veripaque;3,3-bis-(4-hydroxy-phenyl)-indolin-2-one;Oxyphenisatine;
分子式:C20H15NO3
分子量:317.338
精确质量:317.105
Psa:69.56
Logp:3.5223

编号系统

EINECS号:204-728-1

物化性质

密度:1.352g/cm3
沸点:562.9ºC at 760 mmHg
闪点:294.2ºC
折射率:1.691
蒸汽压:2.82E-13mmHg at 25°C

安全信息

海关编码:2933790090

生产方法及用途

生产方法
用靛红与苯酚在浓硫酸作用下缩合制得。 三醋酚汀的中间体。
用途
三醋酚汀的中间体。

合成路线

  • 参考文献

    Song, Hyun Nam; Lee, Hong Jung; Kim, Hyoung Rae; Ryu, Eung K.; Kim, Jae Nyoung Synthetic Communications, 1999 , vol. 29, # 19 p. 3303 - 3311

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图谱

13C NMR : Predict


1H NMR : Predict


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