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化合物简介
Neuroprotective HDAC6 inhibitor.
基本信息
CAS：1239262-52-2
中文别名：
英文别名：N-hydroxy-4-({2-methyl-1H,3H,4H-pyrido[4,3-b]indol-5-yl}methyl)benzamide hydrochloride;N-Hydroxy-4-[(2-methyl-1,2,3,4-tetrahydro-5H-pyrido[4,3-b]indol-5 -yl)methyl]benzamide;TUBASTATIN A_HCL;[4-({2-methyl-1H,2H,3H,4H,5H-pyrido[4,3-b]indol-5-yl}methyl)phenyl]formamido 2,2,2-trifluoroacetate;TUBASTATIN A HYDROCHLORIDE;TUBASTSTINA HCL;TRIETHYLENETHIOPHOSPHORAMIDE,WHITE SOLID;Tubastatin A;TUBASTATIN A ((2-METHYL-3,4-DIHYDRO-1H-PYRIDO[4,3-B]-INDOL- 5(2H)-YL)METHYL)BENZAMIDE);TUBASTANTIN A;Tubastatin A (trifluoroacetate salt);Tubastatin A Trifluoroacetic Acid Salt;
分子式：C22H22F3N3O4
分子量：449.423
精确质量：449.156
Psa：94.8
Logp：3.7586
中文别名：
英文别名：N-hydroxy-4-({2-methyl-1H,3H,4H-pyrido[4,3-b]indol-5-yl}methyl)benzamide hydrochloride;N-Hydroxy-4-[(2-methyl-1,2,3,4-tetrahydro-5H-pyrido[4,3-b]indol-5 -yl)methyl]benzamide;TUBASTATIN A_HCL;[4-({2-methyl-1H,2H,3H,4H,5H-pyrido[4,3-b]indol-5-yl}methyl)phenyl]formamido 2,2,2-trifluoroacetate;TUBASTATIN A HYDROCHLORIDE;TUBASTSTINA HCL;TRIETHYLENETHIOPHOSPHORAMIDE,WHITE SOLID;Tubastatin A;TUBASTATIN A ((2-METHYL-3,4-DIHYDRO-1H-PYRIDO[4,3-B]-INDOL- 5(2H)-YL)METHYL)BENZAMIDE);TUBASTANTIN A;Tubastatin A (trifluoroacetate salt);Tubastatin A Trifluoroacetic Acid Salt;
分子式：C22H22F3N3O4
分子量：449.423
精确质量：449.156
Psa：94.8
Logp：3.7586
编号系统
物化性质
密度：1.3±0.1g/cm3
折射率：1.668
储存条件：室温
折射率：1.668
储存条件：室温
安全信息
生产方法及用途
合成路线
-
参考文献
THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS; KOZIKOWSKI, Alan; BUTLER, Kyle, B.; KALIN, Jay, Hans Patent: WO2011/11186 A2, 2011 ; Location in patent: Page/Page column 54-55 ; WO 2011/011186 A2
上游原料
下游产品
图谱
13C NMR : Predict
1H NMR : Predict
