化学科研者一站式服务平台


  • 利凡斯的明

    rivastigmine

化合物简介

Rivastigmine (sold under the trade name Exelon) is a parasympathomimetic or cholinergic agent for the treatment of mild to moderate dementia of the Alzheimer's type and dementia due to Parkinson's disease. The drug can be administered orally or via a transdermal patch; the latter form reduces the prevalence of side effects, which typically include nausea and vomiting. The drug is eliminated through the urine, and appears to have relatively few drug-drug interactions.

基本信息

CAS:123441-03-2
中文别名:利斯的明;N-乙基-N-甲基-氨基甲酸 3-[(S)-1-(二甲氨基)乙基]苯酯;
英文别名:N-Ethyl-N-methylcarbamic acid 3-[(1S)-1-(dimethylamino)ethyl]phenyl-ester;[3-[(1S)-1-(dimethylamino)ethyl]phenyl] N-ethyl-N-methylcarbamate;Rivastigmine;
分子式:C18H28N2O8
分子量:400.424
精确质量:400.185
Psa:147.84
Logp:0.6371

编号系统

UNII:PKI06M3IW0

物化性质

密度:1.038g/cm3
沸点:316.2ºC at 760mmHg
闪点:145ºC
折射率:1.518
蒸汽压:0.000416mmHg at 25°C

安全信息

生产方法及用途

合成路线

上游原料

下游产品

图谱

13C NMR : Predict


1H NMR : Predict


加载中...