Alendronic acid (INN) or alendronate sodium (USAN) — sold as Fosamax by Merck — is a bisphosphonate drug used for osteoporosis, osteogenesis imperfecta, and several other bone diseases. It is marketed alone as well as in combination with vitamin D (2,800 IU and 5,600 IU, under the name Fosamax+D). Merck's U.S. patent on alendronate expired in 2008 and the drug is now available as a generic. This is the most widely prescribed bisphosphonate medicine in the United States .

CAS：121268-17-5
中文别名：1,1-二甲基-2-甲硫基乙胺;阿仑磷酸钠;(4-氨基-1-羟基-1-膦酸基-丁基)-磷酸钠盐;三水阿仑膦酸钠;阿仑膦酸钠;
英文别名：(4-Amino-1-hydroxy-1-phosphonobutyl)phosphonic Acid Monosodium Salt Trihydrate;Alendronate sodium;4-amino-1-hydroxy-1-phosphonobutyl phosphonic acid,monosodium,Alendronate sodium trihydrate;Monosodium (4-Amino-1-hydroxy-1-phosphonobutyl)phosphonate Trihydrate;Alendronate SodiuM Trihydrate;4-amino-1-hydroxy-1-phosphonobutyl phosphonic acid,monosodium MK-217;Alendronic Acid Monosodium Salt Trihydrate;Alendronate Sodium;Alendronate monosodium trihydrate;Sodium alendronate;
分子式：C4H18NNaO10P2
分子量：325.124
精确质量：325.03
Psa：211.45
Logp：-0.3276

UNII：2UY4M2U3RA

外观与性状：白色结晶固体
密度：1.857g/cm3
沸点：616.7ºC at 760 mmHg
熔点：245°C
闪点：326.7ºC
储存条件：-20ºC

RTECS号：SZ6523500
安全说明：S26; S36
WGK Germany：3
危险类别码：R22; R36/37/38
危险品标志：Xn; Xi
危险标志：GHS07
危险性描述：H302
信号词：Warning

用途
阿仑膦酸钠适用于治疗绝经后妇女的骨质疏松症，以预防髋部和脊柱骨折（椎骨压缩性骨折），也适用于男性骨质疏松症以增加骨量。