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化合物简介
Oxidopamine, also known as 6-hydroxydopamine (6-OHDA) or 2,4,5-trihydroxyphenethylamine, is a neurotoxic synthetic organic compound used by researchers to selectively destroy dopaminergic and noradrenergic neurons in the brain. 6-OHDA is thought to enter the neurons via the dopamine and noradrenaline (norepinephrine) reuptake transporters. Oxidopamine is often used in conjunction with a selective noradrenaline reuptake inhibitor (such as desipramine) to selectively destroy dopaminergic neurons.
基本信息
CAS:1199-18-4
中文别名:
英文别名:1,2,4-BENZENETRIOL,5-(2-AMINOETHYL)-;OXIDOPAMINE HYDROCHLORIDE;5-(2-Aminoethyl)benzene-1,2,4-triol;
分子式:C8H11NO3
分子量:169.178
精确质量:169.074
Psa:86.71
Logp:1.0049
中文别名:
英文别名:1,2,4-BENZENETRIOL,5-(2-AMINOETHYL)-;OXIDOPAMINE HYDROCHLORIDE;5-(2-Aminoethyl)benzene-1,2,4-triol;
分子式:C8H11NO3
分子量:169.178
精确质量:169.074
Psa:86.71
Logp:1.0049
编号系统
EINECS号:214-842-3
RTECS号:DC4580000
RTECS号:DC4580000
物化性质
蒸汽压:3.58E-07mmHg at 25°C
安全信息
海关编码:2922299090
生产方法及用途
合成路线
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参考文献
Tetrahedron Letters, , vol. 40, # 14 p. 2833 - 2836
上游原料
下游产品
图谱
1H NMR : Predict
13C NMR : Predict




