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化合物简介
Tazarotene (marketed as Tazorac, Avage, Zorac, and Fabior) is a third-generation prescription topical retinoid sold as a cream, gel, or foam. Tazarotene is a member of the acetylenic class of retinoids. This medication is approved for treatment of psoriasis, acne, and sun damaged skin (photodamage). It is commonly sold in two concentrations: 0.05% and 0.1%.
基本信息
CAS:118292-40-3
中文别名:6-[2-(4,4-二甲基二氢苯并噻喃-6-基)乙炔基]吡啶-3-甲酸乙酯;
英文别名:Ethyl 6-((4,4-dimethylthiochroman-6-yl)ethynyl)nicotinate;Tazarotene;ethyl 6-[2-(4,4-dimethyl-2,3-dihydrothiochromen-6-yl)ethynyl]pyridine-3-carboxylate;
分子式:C21H21NO2S
分子量:351.462
精确质量:351.129
Psa:64.49
Logp:4.4315
中文别名:6-[2-(4,4-二甲基二氢苯并噻喃-6-基)乙炔基]吡啶-3-甲酸乙酯;
英文别名:Ethyl 6-((4,4-dimethylthiochroman-6-yl)ethynyl)nicotinate;Tazarotene;ethyl 6-[2-(4,4-dimethyl-2,3-dihydrothiochromen-6-yl)ethynyl]pyridine-3-carboxylate;
分子式:C21H21NO2S
分子量:351.462
精确质量:351.129
Psa:64.49
Logp:4.4315
编号系统
MDL号:MFCD00867628
物化性质
外观与性状:白色固体
密度:1.22 g/cm3
沸点:499.8ºC at 760 mmHg
熔点:97-98ºC
闪点:256.1ºC
折射率:1.624
蒸汽压:4.03E-10mmHg at 25°C
密度:1.22 g/cm3
沸点:499.8ºC at 760 mmHg
熔点:97-98ºC
闪点:256.1ºC
折射率:1.624
蒸汽压:4.03E-10mmHg at 25°C
安全信息
海关编码:2942000000
生产方法及用途
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上游原料
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图谱
Predict 1H proton NMR

13C NMR : Predict

1H NMR : Predict
