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  • 北美黄连碱

    (-)-β-HYDRASTINE

化合物简介

Hydrastine is an alkaloid which was discovered in 1851 by Alfred P. Durand. Hydrolysis of hydrastine yields hydrastinine, which was patented by Bayer as a haemostatic drug during the 1910s. It is present in Hydrastis canadensis (thus the name) and other plants of the Ranunculaceae family.

基本信息

CAS:118-08-1
中文别名:(-)-Beta-白毛莨碱;金印草素;
英文别名:1(3H)-Isobenzofuranone, 6,7-dimethoxy-3-(5,6,7,8-tetrahydro-6-methyl-1,3-dioxolo[4,5-g]isoquinolin-5-yl)-, [S-(R*,S*)]-;Hydrastine (10 mg);HYDRASTINE;quinolin-5-yl);(-)-Beta-Hydrastine;Hydrastinebase;(-)-B-HYDIASTINE;l-hydrastine;HYDRASTINE,(-)-B;
分子式:C21H21NO6
分子量:383.395
精确质量:383.137
Psa:66.46
Logp:2.8111

编号系统

EINECS号:204-233-0
RTECS号:MU6030000
MDL号:MFCD00152561
PubChem号:24895532

物化性质

密度:1.339g/cm3
沸点:548.8ºC at 760mmHg
熔点:132ºC
闪点:285.7ºC
折射率:1.614
储存条件:-20ºC
蒸汽压:4.28E-12mmHg at 25°C

安全信息

RTECS号:MU6030000
安全说明:S36
危险类别码:R20/21/22
WGK Germany:3
危险品运输编码:1544
危险类别:6.1(b)
包装等级:III
危险品标志:Xn

生产方法及用途

合成路线

上游原料

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图谱

13C NMR : Predict


1H NMR : Predict


Mass spectrum (electron ionization)


IR : KBr disc


IR : nujol mull


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