1-β-D-Arabinofuranosyluracil-2-C-methyl is an impurity of PSI-7977, a prodrug that is metabolized to the active antiviral agent 2'-deoxy-2'-α-fluoro-β-C-methyluridine-5'-monophosphate and is currently being investigated in phase 3 clinical trials for the treatment of hepatitis C. Studies have profiled PSI-7977 as a nucleotide inhibitor of hepatitis C virus, exerting selective inhibitory effects towards HCV NS5B polymerase.

CAS：114262-49-6
中文别名：
英文别名：.2\'-C-methyl- arabino-uridine;2\'-methyl-1-β-D-arabinofuranosyluracil;Sofosbuvir Impurity 12;
分子式：C10H14N2O6
分子量：258.228
精确质量：258.085
Psa：124.78
Logp：-2.4618