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化合物简介

Dosulepin (INN, BAN) formerly known as dothiepin (USAN), and marketed under the brand names Prothiaden, Dothep, Thaden, and Dopress, is a tricyclic antidepressant that is used in several European and South Asian countries, as well as Australia, South Africa, and New Zealand. It is not used in the United States.

基本信息

CAS:113-53-1
中文别名
英文别名:11-(3-Dimethylamino-propyliden)-6,11-dihydro-dibenzothiepin;Methiaden;Dolsulepine;Prothiadene;Dosulepine;DOTHIEPIN;1-Propanamine, 3-dibenzo[b,e]thiepin-11(6H)-ylidene-N,N-dimethyl-;11-(3-dimethylaminopropylidene)-6,11-dihydrodibenzo(b,e)thiepin;iz914;Prothiaden;Dothep;dosulepin;11(16H)-(3-[dimethylamino]propylidene)dibenz[b,e]thiopine;
分子式:C19H21NS
分子量:295.442
精确质量:295.139
Psa:28.54
Logp:4.6757

编号系统

EINECS号:204-031-2

物化性质

外观与性状:淡黄色低熔点固体
密度:1.148 g/cm3
沸点:430.9ºC at 760 mmHg
熔点:55-57ºC
闪点:214.4ºC
储存条件:Refrigerator

安全信息

危险品运输编码:UN 3249
危险类别:6.1(b)
包装等级:III

生产方法及用途

合成路线

上游原料

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图谱

13C NMR : Predict


1H NMR : Predict


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