Roxindole (EMD-49,980) is a dopaminergic and serotonergic drug which was originally developed for the treatment of schizophrenia. In clinical trials its antipsychotic efficacy was only modest but it was unexpectedly found to produce potent and rapid antidepressant and anxiolytic effects. As a result, roxindole was further researched for the treatment of depression instead. It has also been investigated as a therapy for Parkinson's disease and prolactinoma.

CAS：112192-04-8
中文别名：罗克吲哚;3-[4-(3,6-二氢-4-苯基-1(2H)-吡啶)丁基]-1H-吲哚-5-醇盐酸盐;
英文别名：Roxindole;RoxindoleHCl;Roxindole hydrochloride,3-[4-(3,6-Dihydro-4-phenyl-1(2H)-pyridinyl)butyl]-1H-indol-5-olhydrochloride;ROXINDOLE HYDROCHLORIDE;
分子式：C23H26N2O
分子量：346.465
精确质量：346.205
Psa：39.26
Logp：4.9234

UNII：43227SMS0O

密度：1.173g/cm3
沸点：575.7ºC at 760mmHg
闪点：302ºC
折射率：1.651
蒸汽压：7.46E-14mmHg at 25°C

海关编码：2933990090