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化合物简介

Non-steroidal anti-inflammatory drug (NSAID) with potent anti-inflammatory and analgesic properties approved for veterinary use. It has inhibitory effect on cyclooxygenase and 5-lipxygenase activity as well as inhibiting the production of cytokines in peripheral cells outside the CNS.

基本信息

CAS:103475-41-8
中文别名
英文别名:3-[5-(4-chlorophenyl)-1-(4-methoxyphenyl)-3-pyrazolyl]-N-hydroxy-N-methylpropanamide;Tepoxaline;Tepoxalina;Tepoxalina [Spanish];5-(4-chlorophenyl)-N-hydroxy-1-(4-methoxyphenyl)-N-methyl-1H-pyrazole-3-propanamide;3-[5-(4-chlorophenyl)-1-(4-methoxyphenyl)pyrazol-3-yl]-N-hydroxy-N-methylpropanamide;TEPOXALIN;Tepoxalinum [Latin];Tepoxaline [French];
分子式:C20H20ClN3O3
分子量:385.844
精确质量:385.119
Psa:67.59
Logp:3.9815

编号系统

UNII:TZ4OX61974

物化性质

密度:1.26 g/cm3
沸点:573ºC at 760 mmHg
闪点:300.3ºC
折射率:1.61
蒸汽压:5.72E-14mmHg at 25°C

安全信息

生产方法及用途

用途
抗银屑病。

合成路线

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图谱

1H NMR : Predict


13C NMR : Predict


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