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4-氮杂-5alpha-雄甾-1-烯-3-酮-17beta-羧酸甲酯
methyl (1S,3aS,3bS,5aR,9aR,9bS,11aS)-9a,11a-dimethyl-7-oxo-1,2,3,3a,3b,4,5,5a,6,9b,10,11-dodecahydroindeno[5,4-f]quinoline-1-carboxylate
化合物简介
Finasteride and Dutasteride impurity. An intermediate in the synthesis of Finasteride and Dutasteride, 5α-reductase inhibitors used for treatment of benign prostatic hyperplasia acne, seborrhea, female hirsutism, prostatitis, and prostatic carcinoma and other hyperandrogenetic related disorders. Finasteride impurity.
基本信息
CAS：103335-41-7
中文别名：
英文别名：Methyl 3-oxo-4-aza-5a-androst-1-ene-17beta-carboxylate;Methyl 4-aza-5alpha-Androsta-1-en-3-one-17beta-Carboxylate;3-Oxo-4-aza-5Alpha-Alphandrost-1-ene-17Beta-carboxylic Acid Methyl Ester;(4aR,4bS,6aS,7S,9aS,9bS,11aR)-methyl 4a,6a-dimethyl-2-oxo-2,4a,4b,5,6,6a,7,8,9,9a,9b,10,11,11a-tetradecahydro-1H-indeno[5,4-f]quinoline-7-carboxylate;
分子式：C20H29NO3
分子量：331.449
精确质量：331.215
Psa：55.4
Logp：3.4016
中文别名：
英文别名：Methyl 3-oxo-4-aza-5a-androst-1-ene-17beta-carboxylate;Methyl 4-aza-5alpha-Androsta-1-en-3-one-17beta-Carboxylate;3-Oxo-4-aza-5Alpha-Alphandrost-1-ene-17Beta-carboxylic Acid Methyl Ester;(4aR,4bS,6aS,7S,9aS,9bS,11aR)-methyl 4a,6a-dimethyl-2-oxo-2,4a,4b,5,6,6a,7,8,9,9a,9b,10,11,11a-tetradecahydro-1H-indeno[5,4-f]quinoline-7-carboxylate;
分子式：C20H29NO3
分子量：331.449
精确质量：331.215
Psa：55.4
Logp：3.4016
编号系统
EINECS号：600-422-0
物化性质
外观与性状：灰白色固体
密度：1.114g/cm3
沸点：478.615ºC at 760 mmHg
熔点：280-282ºC (dec.)
闪点：243.258ºC
折射率：1.525
蒸汽压：0mmHg at 25°C
密度：1.114g/cm3
沸点：478.615ºC at 760 mmHg
熔点：280-282ºC (dec.)
闪点：243.258ºC
折射率：1.525
蒸汽压：0mmHg at 25°C
安全信息
生产方法及用途
合成路线
上游原料
下游产品
图谱
13C NMR : Predict
1H NMR : Predict
