化合物简介
基本信息
CAS：102746-01-0
中文别名：
英文别名：
分子式：C22H26N2O4
分子量：382.453
精确质量：382.189
Psa：68.82
Logp：2.1815
编号系统
物化性质
熔点：255 - 256 °C
安全信息
生产方法及用途
合成路线
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(4R,4aR,7R,7aR,12bS,14S)-14-acetamido-7,9-dimethoxy-1,2,7,7a-tetrahydro-7,4a-ethano-4,12-methanobenzofuro[3,2-e]isoquinoline-3(4H)-carboxamide
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参考文献
Lessor, Ralph A.; Bajwa, Balbir S.; Rice, Kenner C.; Jacobson, Arthur E.; Streaty, Richard A.; et al.
Journal of Medicinal Chemistry, 1986, vol. 29, # 11 p. 2136 - 2141
doi: 10.1021/jm00161a002
上游原料
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(4R,4aR,7R,7aR,12bS,14S)-14-acetamido-7,9-dimethoxy-1,2,7,7a-tetrahydro-7,4a-ethano-4,12-methanobenzofuro[3,2-e]isoquinoline-3(4H)-carboxamide
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N-((4R,4aR,7R,7aR,12bS,14S)-3-cyano-7,9-dimethoxy-1,2,3,4,7,7a-hexahydro-7,4a-ethano-4,12-methanobenzofuro[3,2-e]isoquinolin-14-yl)acetamide
下游产品
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(4R,4aR,7R,7aR,12bS,14S)-14-amino-7-methoxy-3-propyl-1,2,3,4,7,7a-hexahydro-7,4a-ethano-4,12-methanobenzofuro[3,2-e]isoquinolin-9-ol
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(4R,4aR,7R,7aR,12bS,14S)-7,9-dimethoxy-3-propyl-1,2,3,4,7,7a-hexahydro-7,4a-ethano-4,12-methanobenzofuro[3,2-e]isoquinolin-14-amine
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(4R,4aR,7R,7aR,12bS,14S)-14-amino-3-(cyclopropylmethyl)-7-methoxy-1,2,3,4,7,7a-hexahydro-7,4a-ethano-4,12-methanobenzofuro[3,2-e]isoquinolin-9-ol
图谱
